Chronic HCV is not the only cause of cirrhosis. There are a lot many reasons for this infectious liver disease. Other conditions like alcoholism, autoimmune disorders, Hepatitis B and other causes can also lead to cirrhosis.
People who have cirrhosis because of HCV have a greater risk of liver cancer. The incidence of liver cancer is increasing in the U.S. Among the cause of cancer deaths in men, liver cancer ranks number five and among women, it is ranked number eight.
In a few cases, HCV leads to liver cancer or severe damage to the liver thereby leading to end of a stage in liver disease and finally failure of the liver. The only treatment that will then be effective is a transplant of the liver.
Primarily, HCV is a liver disease; still the virus can cause other medical problems. These are called as extrahepatic manifestations because they happen outside the liver. We have not been able to discover all the ways that HCV affects the body, here are some that we do know about.